Mechanisms underlying stage-1 TRPL channel translocation in Drosophila photoreceptors.
BACKGROUND:TRP channels function as key mediators of sensory transduction and other cellular signaling pathways.In Drosophila, TRP and TRPL are the light-activated channels in photoreceptors.While TRP is statically localized in the signaling compartment of the cell (the rhabdomere), TRPL localization is regulated by light.TRPL channels translocate